Review



small cell lung cancer cell lines nci h146  (ATCC)


Bioz Verified Symbol ATCC is a verified supplier
Bioz Manufacturer Symbol ATCC manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 95
      Buy from Supplier

    Structured Review

    ATCC small cell lung cancer cell lines nci h146
    (A) mRNA and western blot of MET expression levels in a series of small cell lung cancer cell lines. (B and C) MET expression by flow cytometry and cytotoxicity in NCI-H1341. N= 3 technical replicates in the cytotoxicity assay; P values from two-way ANOVA. (D-E) MET expression by flow cytometry and cytotoxicity in <t>NCI-H146.</t> N= 3 technical replicates; P values calculated using two-way ANOVA. (F) Histogram of MET expression levels in different cell lines. (G) Cytotoxicity of VHH2-CARs against the same cell lines as in (E). N= 3 technical replicates; P values calculated using two-way ANOVA. * P<0.05; **P<0.01; ***P<0.001; ****P<0.0001 .
    Small Cell Lung Cancer Cell Lines Nci H146, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 137 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/small cell lung cancer cell lines nci h146/product/ATCC
    Average 95 stars, based on 137 article reviews
    small cell lung cancer cell lines nci h146 - by Bioz Stars, 2026-03
    95/100 stars

    Images

    1) Product Images from "Nanobody MET CAR T cells show efficacy in solid tumors"

    Article Title: Nanobody MET CAR T cells show efficacy in solid tumors

    Journal: bioRxiv

    doi: 10.64898/2026.01.27.702111

    (A) mRNA and western blot of MET expression levels in a series of small cell lung cancer cell lines. (B and C) MET expression by flow cytometry and cytotoxicity in NCI-H1341. N= 3 technical replicates in the cytotoxicity assay; P values from two-way ANOVA. (D-E) MET expression by flow cytometry and cytotoxicity in NCI-H146. N= 3 technical replicates; P values calculated using two-way ANOVA. (F) Histogram of MET expression levels in different cell lines. (G) Cytotoxicity of VHH2-CARs against the same cell lines as in (E). N= 3 technical replicates; P values calculated using two-way ANOVA. * P<0.05; **P<0.01; ***P<0.001; ****P<0.0001 .
    Figure Legend Snippet: (A) mRNA and western blot of MET expression levels in a series of small cell lung cancer cell lines. (B and C) MET expression by flow cytometry and cytotoxicity in NCI-H1341. N= 3 technical replicates in the cytotoxicity assay; P values from two-way ANOVA. (D-E) MET expression by flow cytometry and cytotoxicity in NCI-H146. N= 3 technical replicates; P values calculated using two-way ANOVA. (F) Histogram of MET expression levels in different cell lines. (G) Cytotoxicity of VHH2-CARs against the same cell lines as in (E). N= 3 technical replicates; P values calculated using two-way ANOVA. * P<0.05; **P<0.01; ***P<0.001; ****P<0.0001 .

    Techniques Used: Western Blot, Expressing, Flow Cytometry, Cytotoxicity Assay



    Similar Products

    small cell lung cancer cell lines nci h146  (ATCC)
    95
    ATCC small cell lung cancer cell lines nci h146
    (A) mRNA and western blot of MET expression levels in a series of small cell lung cancer cell lines. (B and C) MET expression by flow cytometry and cytotoxicity in NCI-H1341. N= 3 technical replicates in the cytotoxicity assay; P values from two-way ANOVA. (D-E) MET expression by flow cytometry and cytotoxicity in <t>NCI-H146.</t> N= 3 technical replicates; P values calculated using two-way ANOVA. (F) Histogram of MET expression levels in different cell lines. (G) Cytotoxicity of VHH2-CARs against the same cell lines as in (E). N= 3 technical replicates; P values calculated using two-way ANOVA. * P<0.05; **P<0.01; ***P<0.001; ****P<0.0001 .
    Small Cell Lung Cancer Cell Lines Nci H146, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/small cell lung cancer cell lines nci h146/product/ATCC
    Average 95 stars, based on 1 article reviews
    small cell lung cancer cell lines nci h146 - by Bioz Stars, 2026-03
    95/100 stars
    		  Buy from Supplier
    nci h146  (ATCC)
    95
    ATCC nci h146
    (A) mRNA and western blot of MET expression levels in a series of small cell lung cancer cell lines. (B and C) MET expression by flow cytometry and cytotoxicity in NCI-H1341. N= 3 technical replicates in the cytotoxicity assay; P values from two-way ANOVA. (D-E) MET expression by flow cytometry and cytotoxicity in <t>NCI-H146.</t> N= 3 technical replicates; P values calculated using two-way ANOVA. (F) Histogram of MET expression levels in different cell lines. (G) Cytotoxicity of VHH2-CARs against the same cell lines as in (E). N= 3 technical replicates; P values calculated using two-way ANOVA. * P<0.05; **P<0.01; ***P<0.001; ****P<0.0001 .
    Nci H146, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/nci h146/product/ATCC
    Average 95 stars, based on 1 article reviews
    nci h146 - by Bioz Stars, 2026-03
    95/100 stars
    		  Buy from Supplier
    sclc cell lines nci h146  (ATCC)
    95
    ATCC sclc cell lines nci h146
    (A) mRNA and western blot of MET expression levels in a series of small cell lung cancer cell lines. (B and C) MET expression by flow cytometry and cytotoxicity in NCI-H1341. N= 3 technical replicates in the cytotoxicity assay; P values from two-way ANOVA. (D-E) MET expression by flow cytometry and cytotoxicity in <t>NCI-H146.</t> N= 3 technical replicates; P values calculated using two-way ANOVA. (F) Histogram of MET expression levels in different cell lines. (G) Cytotoxicity of VHH2-CARs against the same cell lines as in (E). N= 3 technical replicates; P values calculated using two-way ANOVA. * P<0.05; **P<0.01; ***P<0.001; ****P<0.0001 .
    Sclc Cell Lines Nci H146, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/sclc cell lines nci h146/product/ATCC
    Average 95 stars, based on 1 article reviews
    sclc cell lines nci h146 - by Bioz Stars, 2026-03
    95/100 stars
    		  Buy from Supplier
    htb  (ATCC)
    95
    ATCC htb
    (A) mRNA and western blot of MET expression levels in a series of small cell lung cancer cell lines. (B and C) MET expression by flow cytometry and cytotoxicity in NCI-H1341. N= 3 technical replicates in the cytotoxicity assay; P values from two-way ANOVA. (D-E) MET expression by flow cytometry and cytotoxicity in <t>NCI-H146.</t> N= 3 technical replicates; P values calculated using two-way ANOVA. (F) Histogram of MET expression levels in different cell lines. (G) Cytotoxicity of VHH2-CARs against the same cell lines as in (E). N= 3 technical replicates; P values calculated using two-way ANOVA. * P<0.05; **P<0.01; ***P<0.001; ****P<0.0001 .
    Htb, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/htb/product/ATCC
    Average 95 stars, based on 1 article reviews
    htb - by Bioz Stars, 2026-03
    95/100 stars
    		  Buy from Supplier
    human sclc cell lines h146 htb 173  (ATCC)
    95
    ATCC human sclc cell lines h146 htb 173
    (A) mRNA and western blot of MET expression levels in a series of small cell lung cancer cell lines. (B and C) MET expression by flow cytometry and cytotoxicity in NCI-H1341. N= 3 technical replicates in the cytotoxicity assay; P values from two-way ANOVA. (D-E) MET expression by flow cytometry and cytotoxicity in <t>NCI-H146.</t> N= 3 technical replicates; P values calculated using two-way ANOVA. (F) Histogram of MET expression levels in different cell lines. (G) Cytotoxicity of VHH2-CARs against the same cell lines as in (E). N= 3 technical replicates; P values calculated using two-way ANOVA. * P<0.05; **P<0.01; ***P<0.001; ****P<0.0001 .
    Human Sclc Cell Lines H146 Htb 173, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human sclc cell lines h146 htb 173/product/ATCC
    Average 95 stars, based on 1 article reviews
    human sclc cell lines h146 htb 173 - by Bioz Stars, 2026-03
    95/100 stars
    		  Buy from Supplier
    h524  (ATCC)
    95
    ATCC h524
    A Cell surface DLK1 expression by flow cytometry in 3 small cell lung cancer (SCLC) cell lines <t>(H524,</t> H146, and H1436) (data representative of n = 3 independent experiments). B DLK1 molecules/cell relative to DLL3 among SCLC cell lines ( n = 3 independent experiments). Error bars represent mean values ± S.E.M . C Flow cytometry histograms assessing ABCB1 in SCLC cell lines (data representative of n = 3 independent experiments). D SG3199 cytotoxicity in SCLC cell lines. Cells were treated with SG3199 for 3 days (data representative of n = 4 independent experiments). E ADCT-701 cytotoxicity among SCLC cell lines. Cells were treated with ADCT-701 or B12-PL1601 for 7 days (data representative of n = 4 independent experiments). F Tumor growth curves of SCLC xenograft models after treatment (1 mg/kg) with saline (H524: n = 5; H146: n = 5; H1436: n = 6), B12-PL1601 (H524: n = 5; H146: n = 4; H1436: n = 7) or ADCT-701 (H524: n = 4; H146: n = 6; H1436: n = 7) when tumor size reached an average of 100–150 mm 3 . Arrows indicate re-treatment with ADCT-701. Scale bars represent 200 μm. Error bars represent mean values ± S.E.M. Source data are provided as a Source Data file.
    H524, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/h524/product/ATCC
    Average 95 stars, based on 1 article reviews
    h524 - by Bioz Stars, 2026-03
    95/100 stars
    		  Buy from Supplier

    Image Search Results


    (A) mRNA and western blot of MET expression levels in a series of small cell lung cancer cell lines. (B and C) MET expression by flow cytometry and cytotoxicity in NCI-H1341. N= 3 technical replicates in the cytotoxicity assay; P values from two-way ANOVA. (D-E) MET expression by flow cytometry and cytotoxicity in NCI-H146. N= 3 technical replicates; P values calculated using two-way ANOVA. (F) Histogram of MET expression levels in different cell lines. (G) Cytotoxicity of VHH2-CARs against the same cell lines as in (E). N= 3 technical replicates; P values calculated using two-way ANOVA. * P<0.05; **P<0.01; ***P<0.001; ****P<0.0001 .

    Journal: bioRxiv

    Article Title: Nanobody MET CAR T cells show efficacy in solid tumors

    doi: 10.64898/2026.01.27.702111

    Figure Lengend Snippet: (A) mRNA and western blot of MET expression levels in a series of small cell lung cancer cell lines. (B and C) MET expression by flow cytometry and cytotoxicity in NCI-H1341. N= 3 technical replicates in the cytotoxicity assay; P values from two-way ANOVA. (D-E) MET expression by flow cytometry and cytotoxicity in NCI-H146. N= 3 technical replicates; P values calculated using two-way ANOVA. (F) Histogram of MET expression levels in different cell lines. (G) Cytotoxicity of VHH2-CARs against the same cell lines as in (E). N= 3 technical replicates; P values calculated using two-way ANOVA. * P<0.05; **P<0.01; ***P<0.001; ****P<0.0001 .

    Article Snippet: Small cell lung cancer cell lines NCI-H146 (ATCC HB173) and NCI-H1341(ATCC CRL-5864) were cultured in DMEM-F12 supplemented with 10% FBS, 1X Insulin-Transferrin-Selenium and 1% penicillin/streptomycin.

    Techniques: Western Blot, Expressing, Flow Cytometry, Cytotoxicity Assay

    A Cell surface DLK1 expression by flow cytometry in 3 small cell lung cancer (SCLC) cell lines (H524, H146, and H1436) (data representative of n = 3 independent experiments). B DLK1 molecules/cell relative to DLL3 among SCLC cell lines ( n = 3 independent experiments). Error bars represent mean values ± S.E.M . C Flow cytometry histograms assessing ABCB1 in SCLC cell lines (data representative of n = 3 independent experiments). D SG3199 cytotoxicity in SCLC cell lines. Cells were treated with SG3199 for 3 days (data representative of n = 4 independent experiments). E ADCT-701 cytotoxicity among SCLC cell lines. Cells were treated with ADCT-701 or B12-PL1601 for 7 days (data representative of n = 4 independent experiments). F Tumor growth curves of SCLC xenograft models after treatment (1 mg/kg) with saline (H524: n = 5; H146: n = 5; H1436: n = 6), B12-PL1601 (H524: n = 5; H146: n = 4; H1436: n = 7) or ADCT-701 (H524: n = 4; H146: n = 6; H1436: n = 7) when tumor size reached an average of 100–150 mm 3 . Arrows indicate re-treatment with ADCT-701. Scale bars represent 200 μm. Error bars represent mean values ± S.E.M. Source data are provided as a Source Data file.

    Journal: Nature Communications

    Article Title: Identification of the Notch ligand DLK1 as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma

    doi: 10.1038/s41467-025-60649-w

    Figure Lengend Snippet: A Cell surface DLK1 expression by flow cytometry in 3 small cell lung cancer (SCLC) cell lines (H524, H146, and H1436) (data representative of n = 3 independent experiments). B DLK1 molecules/cell relative to DLL3 among SCLC cell lines ( n = 3 independent experiments). Error bars represent mean values ± S.E.M . C Flow cytometry histograms assessing ABCB1 in SCLC cell lines (data representative of n = 3 independent experiments). D SG3199 cytotoxicity in SCLC cell lines. Cells were treated with SG3199 for 3 days (data representative of n = 4 independent experiments). E ADCT-701 cytotoxicity among SCLC cell lines. Cells were treated with ADCT-701 or B12-PL1601 for 7 days (data representative of n = 4 independent experiments). F Tumor growth curves of SCLC xenograft models after treatment (1 mg/kg) with saline (H524: n = 5; H146: n = 5; H1436: n = 6), B12-PL1601 (H524: n = 5; H146: n = 4; H1436: n = 7) or ADCT-701 (H524: n = 4; H146: n = 6; H1436: n = 7) when tumor size reached an average of 100–150 mm 3 . Arrows indicate re-treatment with ADCT-701. Scale bars represent 200 μm. Error bars represent mean values ± S.E.M. Source data are provided as a Source Data file.

    Article Snippet: Human SCLC cell lines H146 (HTB-173) and H524 (CRL-5831) were obtained from ATCC.

    Techniques: Expressing, Flow Cytometry, Saline